| Bioactivity | ω-Conotoxin FVIA is an N-type Ca2+channel (Ca v 2.2)inhibitor. ω-Conotoxin FVIA reduces mechanical and thermal pain abnormalitiesin a rat model of caudal nerve injury. ω-Conotoxin FVIA can be used in thestudy of highly effective pain relievers with low side effects[1]. |
| Name | ω-Conotoxin FVIA |
| Sequence | Cys-Lys-Gly-Thr-Gly-Lys-Ser-Cys-Ser-Arg-Ile-Ala-Tyr-Asn-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys-NH2 (Disulfide bridge:Cys1-Cys16, Cys8-Cys20, Cys15-Cys25) |
| Shortening | CKGTGKSCSRIAYNCCTGSCRSGKC-NH2 (Disulfide bridge:Cys1-Cys16, Cys8-Cys20, Cys15-Cys25) |
| Formula | C98H164N36O33S6 |
| Molar Mass | 2566.96 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lee S, et al Analgesic effect of highly reversible ω-conotoxin FVIA on N type Ca2+ channels. Mol Pain. 2010 Dec 21;6:97. |