| Bioactivity | μ-Conotoxin PIIIA is a sodium channel (NaV 1.4) blocker. μ-Conotoxin PIIIA can be isolated from Conus purpurascens[1][2]. |
| Target | NaV1.4 Channel |
| Name | μ-Conotoxin PIIIA |
| CAS | 184840-20-8 |
| Sequence | {Pyr}-Arg-Leu-Cys-Cys-Gly-Phe-{Hyp}-Lys-Ser-Cys-Arg-Ser-Arg-Gln-Cys-Lys-{Hyp}-His-Arg-Cys-Cys-NH2 (Disulfide bridge: Cys4-Cys16, Cys5-Cys21 and Cys11-Cys22) |
| Shortening | {Pyr}-RLCCGF-{Hyp}-KSCRSRQCK-{Hyp}-HRCC-NH2 (Disulfide bridge: Cys4-Cys16, Cys5-Cys21 and Cys11-Cys22) |
| Formula | C103H166N40O28S6 |
| Molar Mass | 2605.06 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tietze AA, et al. Structurally diverse μ-conotoxin PIIIA isomers block sodium channel NaV 1.4. Angew Chem Int Ed Engl. 2012 Apr 23;51(17):4058-61. |
μ-Conotoxin PIIIA
CAS: 184840-20-8 F: C103H166N40O28S6 W: 2605.06
μ-Conotoxin PIIIA is a sodium channel (NaV 1.4) blocker. μ-Conotoxin PIIIA can be isolated from Conus purpurascens.
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