| Bioactivity | α-Synuclein 4554W is an inhibitor of α-Synuclein (aSyn) aggregation with associated toxicity. α-Synuclein 4554W consists of GIVNGVKA sequences, previously identified through intracellular library screening. α-Synuclein 4554W reduces fibril formation of aSyn mutants assocaited with Parkinson’s disease[1]. |
| Name | α-Synuclein 4554W |
| CAS | 2243207-00-1 |
| Sequence | Ac-Lys-Asp-Gly-Ile-Val-Asn-Gly-Val-Lys-Ala-NH2 |
| Shortening | Ac-KDGIVNGVKA-NH2 |
| Formula | C45H80N14O14 |
| Molar Mass | 1041.20 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Torpey J H, et al. Insights into peptide inhibition of alpha-synuclein aggregation[J]. Frontiers in Neuroscience, 2020, 14: 561462. |
α-Synuclein 4554W
CAS: 2243207-00-1 F: C45H80N14O14 W: 1041.20
α-Synuclein 4554W is an inhibitor of α-Synuclein (aSyn) aggregation with associated toxicity. α-Synuclein 4554W consi
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