| Bioactivity | α-Conotoxin MrIC is an α7nAChR biased agonist. α-Conotoxin MrIC exclusively activates α7nAChR regulated by type II positive allosteric modulators, including PNU120596. α-Conotoxin MrIC can be used to study neurological diseases and also to probe the pharmacological properties of α7nAChR[1]. |
| Target | α7nAChR. |
| Name | α-Conotoxin MrIC |
| CAS | 1417816-41-1 |
| Sequence | Pro-Glu-Cys-Cys-Thr-His-Pro-Ala-Cys-His-Val-Ser-Asn-Pro-Glu-Leu-Cys-NH2 (Disulfide bridge:Cys3-Cys9, Cys4-Cys17) |
| Shortening | PECCTHPACHVSNPELC-NH2 (Disulfide bridge:Cys3-Cys9, Cys4-Cys17) |
| Formula | C74H111N23O24S4 |
| Molar Mass | 1835.07 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mueller A, et al. α-Conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors. Biochem Pharmacol. 2015 Mar 15;94(2):155-63. |
α-Conotoxin MrIC
CAS: 1417816-41-1 F: C74H111N23O24S4 W: 1835.07
α-Conotoxin MrIC is an α7nAChR biased agonist. α-Conotoxin MrIC exclusively activates α7nAChR regulated by type II p
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.