| Bioactivity | tau/Aβ40 aggregation-IN-1 (Compound 20) is a tau and Aβ40 aggregation inhibitor with IC50s of 1.8 μM and 1.3 μM, respectively[1]. |
| Invitro | tau/Aβ40 aggregation-IN-1 (Compound 20; 0.1-10 μM; 24 h) 在 SH-SY5Y 细胞中显示出对冈田酸 (HY-N6785) 诱导的 tau 毒性的神经保护作用[1] 。 tau/Aβ40 aggregation-IN-1 抑制电鳗 AChE、人 AChE 和马血清 BChE，IC50 分别为 4.4、16.10 和 0.96 μM。tau/Aβ40 aggregation-IN-1 在 10 μM 对人 BChE 有16% 的抑制作用[1]。 Cell Viability Assay[1] Cell Line: |
| Name | tau/Aβ40 aggregation-IN-1 |
| Formula | C23H28N2O2S |
| Molar Mass | 396.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tonelli M, et al. Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease. Eur J Med Chem. 2023 Mar 15;250:115169. |
tau/Aβ40 aggregation-IN-1
CAS: F: C23H28N2O2S W: 396.55
tau/Aβ40 aggregation-IN-1 (Compound 20) is a tau and Aβ40 aggregation inhibitor with IC50s of 1.8 μM and 1.3 μM, res
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.