PeptideDB

Influenza virus-IN-7

CAS: 2703046-92-6 F: C29H26F2N4O7S W: 612.60

Influenza virus-IN-7 (Example 16) is an orally active cap-dependent endonuclease inhibitor that can be used for the rese
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Bioactivity Influenza virus-IN-7 (Example 16) is an orally active cap-dependent endonuclease inhibitor that can be used for the research of influenza viral infectious diseases[1].
Target IC50: Cap-dependent endonuclease
Invitro Influenza virus-IN-7 (Example 16) 在 MDCK 细胞中显示出对流感 A/Weiss/43(H1N1) 病毒的抗病毒活性,EC50 为 1000 nM)[1]。
In Vivo Influenza virus-IN-7 (Example 16; 5 mg/kg; i.g.; twice daily for 5 days) 可提高 WSN/33 (H1N1) 感染小鼠模型的存活率[1]。 Animal Model:
Name Influenza virus-IN-7
CAS 2703046-92-6
Formula C29H26F2N4O7S
Molar Mass 612.60
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Wang Shen, et al. Polycyclic pyridopyridazine amide oxime-containing carbocyclic derivatives and uses thereof. Patent CN114315827A.