| Bioactivity | hCAIX-IN-13 (Pt2) is an inhibitor of CAIX (arbonic anhydrase IX) with an IC50 value of 6.57 μM. hCAIX-IN-13 inhibits growth of cancer cells and induces cell apoptosis, it can be used for the research of cancer[1]. |
| Invitro | hCAIX-IN-13 (10 and 20 μM; 24 h) effectively attenuates extracellular acidification through the inhibited activity of the cellular CAIX expression[1]. hCAIX-IN-13 (20 and 40 μM; 24 h) affects CAIX expression[1]. hCAIX-IN-13 (0-200 μM; 24 h) shows high cytotoxicity to cancer cell lines[1].hCAIX-IN-13 (5-15 μM; 24 h) promotes the production of cellular ROS[1]. hCAIX-IN-13 (5-20 μM; 48 h) induces cell apoptosis[1]. Western Blot Analysis[1] Cell Line: |
| Name | hCAIX-IN-13 |
| CAS | 2813334-66-4 |
| Formula | C37H33F3N6O7PtS2 |
| Molar Mass | 989.90 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |