| Bioactivity | Topoisomerase II inhibitor 9 (Compound 19b) is a Topo II inhibitor with an IC50 of 0.97 μM. Topoisomerase II inhibitor 9 is also a classical DNA-intercalator with an IC50 of 43.51 μM. Topoisomerase II inhibitor 9 arrests the cell cycle at the G2/M phase and induces apoptosis in Hep G‐2 cells[1]. |
| Invitro | Topoisomerase II inhibitor 9 (Compound 19b) shows antiproliferative activity with IC50 values of 0.50 ± 0.1, 0.75 ± 0.1 and 2.91 ± 0.1 μM against Hep G‐2, Hep‐2 and Caco‐2 cells, respectively[1]. |
| Name | Topoisomerase II inhibitor 9 |
| CAS | 2413901-61-6 |
| Formula | C22H17N7O3S2 |
| Molar Mass | 491.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Topoisomerase II inhibitor 9
CAS: 2413901-61-6 F: C22H17N7O3S2 W: 491.55
Topoisomerase II inhibitor 9 (Compound 19b) is a Topo II inhibitor with an IC50 of 0.97 μM. Topoisomerase II inhibitor
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This product is for research use only, not for human use. We do not sell to patients.