| Bioactivity | eIF4A3-IN-14 (compound 51) is a silvestrol (HY-13251) analogue. eIF4A3-IN-14 interferes the assembling of eIF4F translation complex with EC50s of 40 and 50 nM for myc-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-14 can be used for the research of human cancer pathogenesis[1]. |
| Name | eIF4A3-IN-14 |
| CAS | 1402931-65-0 |
| Formula | C27H27NO7 |
| Molar Mass | 477.51 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Liu T, et al. Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors. J Med Chem. 2012 Oct 25;55(20):8859-78. |
eIF4A3-IN-14
CAS: 1402931-65-0 F: C27H27NO7 W: 477.51
eIF4A3-IN-14 (compound 51) is a silvestrol(HY-13251) analogue. eIF4A3-IN-14 interferes the assembling of eIF4F translati
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.