| Bioactivity | eIF4A3-IN-15 (compound 52) is a silvestrol (HY-13251) analogue. eIF4A3-IN-15 interferes the assembling of eIF4F translation complex with EC50s of 11, 700 and 120 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-15 can be used for the research of human cancer pathogenesis[1]. |
| Name | eIF4A3-IN-15 |
| CAS | 1402931-66-1 |
| Formula | C28H29NO7 |
| Molar Mass | 491.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Liu T, et al. Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors. J Med Chem. 2012 Oct 25;55(20):8859-78. |
eIF4A3-IN-15
CAS: 1402931-66-1 F: C28H29NO7 W: 491.53
eIF4A3-IN-15 (compound 52) is a silvestrol(HY-13251) analogue. eIF4A3-IN-15 interferes the assembling of eIF4F translati
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.