| Bioactivity | ZM226600 is an ATP-sensitive potassium channel opener (EC50: 500 nM). ZM226600 inhibits bladder spontaneous activity[1][2]. |
| Invitro | ZM226600 (1 μM, 30 min) 抑制膀胱自发活动[1]. |
| In Vivo | ZM226600 (10-1000 nmol/kg，静脉注射) 不会显着改变麻醉大鼠的心跳率[1]。 |
| Name | ZM226600 |
| CAS | 147695-92-9 |
| Formula | C16H14F3NO4S |
| Molar Mass | 373.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pinna C,et al. Effect of the ATP-sensitive potassium channel opener ZM226600 on cystometric parameters in rats with ligature-intact, partial urethral obstruction. Eur J Pharmacol. 2005 May 23;516(1):71-7. [2]. Grant TL, et al. Anilide tertiary carbinols: a novel series of K+ channel openers. Trends Pharmacol Sci. 1994 Nov;15(11):402-4. |