Bioactivity | Z36-MP5 is an Mi-2β-targeted inhibitor, with IC50 of 0.082 μM. Z36-MP5 can reduce Mi-2β ATPase activity and reactivates ISG transcription. Z36-MP5 can stimulate T-cell-mediated cytotoxicity[1]. |
CAS | 2839660-03-4 |
Formula | C22H21N5O2 |
Molar Mass | 387.43 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Cang Li, et al. Mi-2β promotes immune evasion in melanoma by activating EZH2 methylation. Nat Commun. 2024 Mar 9;15(1):2163. |