| Bioactivity | Vincristine-d3 (sulfate)is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM[1][2]. |
| Invitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| Name | Vincristine-d3 (sulfate) |
| CAS | 1246817-10-6 |
| Formula | C46H55D3N4O14S |
| Molar Mass | 926.05 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Vincristine-d3 (sulfate)
CAS: 1246817-10-6 F: C46H55D3N4O14S W: 926.05
Vincristine-d3 (sulfate)is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid
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