Bioactivity | (2E)-OBAA is a potent phospholipase A2 (PLA2) inhibitor, with an IC50 of 70 nM. (2E)-OBAA induces apoptosis of HUVEC cells. (2E)-OBAA blocks Melittin-induced Ca2+ influx in Trypanosoma brucei, with an IC50 of 0.4 μM[1][2][3][4]. |
Invitro | (2E)-OBAA (5.7 μM) induces apoptotic cell death of human umbilical vein endothelial cells (HUVEC). After 16 h of treatment, almost all of the cells has disintegrated into apoptotic bodies[1]. |
Name | (2E)-OBAA |
CAS | 221632-26-4 |
Formula | C28H44O3 |
Molar Mass | 428.65 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |