Bioactivity | Valnemulin is an orally active broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria, anaerobic bacteria, Mycoplasma, and Spirochetes. Valnemulin ameliorates enteric diseases, acute polyarthritis and enzootic pneumonia in pigs[1]. Valnemulin exhibits anti-inflammatory efficacy against lipopolysaccharide (HY-D1056)-induced lung injury[2]. |
Invitro | Valnemulin 对 Mycoplasma hyopneumoniae 和 Mycoplasma hyosynoviae 具有抗菌活性,MIC90 分别为 0.0005 μg/mL 和 0.0001 到 0.00025 μg/mL[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Valnemulin 相关抗体: |
In Vivo | Valnemulin (100 mg/kg,灌胃,单剂量) 对 LPS 诱导的 BALB/c 小鼠急性肺损伤具有肺保护作用[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
CAS | 101312-92-9 |
Formula | C31H52N2O5S |
Molar Mass | 564.82 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Hannan PC, et al., In vitro susceptibilities of recent field isolates of Mycoplasma hyopneumoniae and Mycoplasma hyosynoviae to valnemulin (Econor), tiamulin and enrofloxacin and the in vitro development of resistance to certain antimicrobial agents in Mycoplasma hyopneumoniae. Res Vet Sci. 1997 Sep-Oct;63(2):157-60. [2]. Chen Z, et al., Preventive effects of valnemulin on lipopolysaccharide-induced acute lung injury in mice. Inflammation. 2010 Oct;33(5):306-14. |