Bioactivity | UNC8900 is a VHL recruiting STING PROTAC degrader (DC50: 0.0.924 μM). UNC8900 can be used for research of viral or bacterial infection. (Blue: VHL ligand, black: linker; Pink: STING inhibitor)[1]. |
Invitro | UNC8900 (3 μM, 8 h) induces STING protein expression in HKC-8 cells[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> UNC8900 相关抗体: |
Formula | C75H99N17O15S |
Molar Mass | 1510.76 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zhu Z, et al. Development of VHL-recruiting STING PROTACs that suppress innate immunity. Cell Mol Life Sci. 2023 May 14;80(6):149. |