11-Deoxy-16,16-dimethyl-PGE2_product_DataBase

Bioactivity	11-Deoxy-16,16-dimethyl-PGE2, a Prostaglandin E2 analog, is a EP2 and EP3 receptors agonist. 11-Deoxy-16,16-dimethyl-PGE2 protects proximal renal tubular epithelial cells from potent nephrotoxicity-induced cell damage by exerting anti-oxidative stress[1][2].
Invitro	11-Deoxy-16,16-dimethyl-PGE2，选择性刺激多种蛋白质的合成，保护肾近端肾小管上皮 (LLC-PK1) 细胞，包括内皮肌动蛋白结合蛋白、肌球蛋白、伸长因子 2 (EF-2)、伸长因子 1alpha-1 (EF-1alpha)、HSP90beta、GRP78、膜组织延伸刺突蛋白和肌动蛋白[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> 11-Deoxy-16,16-dimethyl-PGE2 相关抗体:
CAS	53658-98-3
Formula	C22H36O4
Molar Mass	364.52
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. R F Parrott, et al. Effects of centrally administered prostaglandin EP receptor agonists on febrile and adrenocortical responses in the prepubertal pig. Brain Res Bull. 1996;41(2):97-103. [2]. Kelly M Towndrow, et al. 11-Deoxy,16,16-dimethyl prostaglandin E2 induces specific proteins in association with its ability to protect against oxidative stress. Chem Res Toxicol. 2003 Mar;16(3):312-9.

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