Bioactivity | Topoisomerase II inhibitor 20 (Compound 3e) is a potent topoisomerase II (Topoisomerase II) inhibitor with an IC50 of 0.98 µM. Topoisomerase II inhibitor 20 induces apoptosis and has broad-spectrum anticancer activity[1]. |
Invitro | Topoisomerase II inhibitor 20 (1.90 µM; 24 h) 表现出细胞阻滞在G2-M期,从而抑制细胞增殖并诱导细胞凋亡[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Topoisomerase II inhibitor 20 相关抗体: Cell Cycle Analysis[1] Cell Line: |
Formula | C22H23F2N5O2S |
Molar Mass | 459.51 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Adly ME, et al. Design, synthesis and in vitro anticancer activity of some new lomefloxacin derivatives. Sci Rep. 2024 Mar 14;14(1):6175 |