| Bioactivity | β-Glucuronidase responsive conjugate 1 (compound 3) is a well-balanced photosensitizer which has photodynamic activity. β-Glucuronidase responsive conjugate 1 inhibits T-24 cell viability and growth with an IC50 of 0.2 μM. β-Glucuronidase responsive conjugate 1 can used to study bladder cancers[1]. |
| Invitro | β-Glucuronidase responsive conjugate 1 (0.01 μM, 24 h) 抑制 T-24 细胞的活力[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> β-Glucuronidase responsive conjugate 1 相关抗体: Cell Viability Assay[1] Cell Line: |
| Formula | C108H127FN16O34Zn |
| Molar Mass | 2277.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Otvagin VF, et al. A first-in-class β-glucuronidase responsive conjugate for selective dual targeted and photodynamic therapy of bladder cancer. Eur J Med Chem. 2024 Mar 5;269:116283. |
β-Glucuronidase responsive conjugate 1
CAS: F: C108H127FN16O34Zn W: 2277.63
β-Glucuronidase responsive conjugate 1 (compound 3) is a well-balanced photosensitizer which has photodynamic activity.
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