PeptideDB

Epiallopregnanolone

CAS: 567-01-1 F: C21H34O3 W: 334.49

Epiallopregnanolone (5α,3β-THDOC), a 3β-hydroxy neurosteroid, an antagonist at GABAA receptors and a NMDA receptor en
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Bioactivity Epiallopregnanolone (5α,3β-THDOC), a 3β-hydroxy neurosteroid, an antagonist at GABAA receptors and a NMDA receptor enhancer[1].
In Vivo Epiallopregnanolone (5α,3β-THDOC; 1-100 mg/kg; ip) 抑制毛果芸香碱引起的小鼠癫痫发作(ED50 为 45.9 mg/kg)[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
CAS 567-01-1
Formula C21H34O3
Molar Mass 334.49
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Brett C Ginsburg, et al. Alphaxalone and epiallopregnanolone in rats trained to discriminate ethanol. Alcohol Clin Exp Res. 2005 Sep;29(9):1621-9.