Bioactivity | Epiallopregnanolone (5α,3β-THDOC), a 3β-hydroxy neurosteroid, an antagonist at GABAA receptors and a NMDA receptor enhancer[1]. |
In Vivo | Epiallopregnanolone (5α,3β-THDOC; 1-100 mg/kg; ip) 抑制毛果芸香碱引起的小鼠癫痫发作(ED50 为 45.9 mg/kg)[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
CAS | 567-01-1 |
Formula | C21H34O3 |
Molar Mass | 334.49 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Brett C Ginsburg, et al. Alphaxalone and epiallopregnanolone in rats trained to discriminate ethanol. Alcohol Clin Exp Res. 2005 Sep;29(9):1621-9. |