Bioactivity | Taltirelin (TA0910) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R) with an IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release)[1]. | ||||||||||||
Target | IC50: 910 nM (Thyrotropin-releasing hormone receptor) | ||||||||||||
Name | Taltirelin | ||||||||||||
CAS | 103300-74-9 | ||||||||||||
Formula | C17H23N7O5 | ||||||||||||
Molar Mass | 405.41 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Thirunarayanan N, et al. Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor. Front Endocrinol (Lausanne). 2012 Oct 9;3:120. |