| Bioactivity | TMX-2172 is a PROTACs degrader for CDK2 and CDK5, with the IC50s of 6.5 and 6.8 nM, respectively. TMX-2172 plays an important role in cancer research (Blue: E3 ligase ligand (HY-W008352); Pink: target protein ligand (HY-170748); Black: linker (HY-151072))[1]. |
| CAS | 2488892-09-5 |
| Formula | C41H45BrFN9O11S |
| Molar Mass | 970.82 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mingxing Teng, et al. Development of CDK2 and CDK5 Dual Degrader TMX-2172. Angew Chem Int Ed Engl. 2020 Aug 10;59(33):13865-13870. |
TMX-2172
CAS: 2488892-09-5 F: C41H45BrFN9O11S W: 970.82
TMX-2172 is a PROTACs degrader for CDK2 and CDK5, with the IC50s of 6.5 and 6.8 nM, respectively. TMX-2172 plays an impo
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