| Bioactivity | MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection[1]. |
| CAS | 1260620-30-1 |
| Sequence | Ac-Glu-Phe-Gln-Leu-Gln-{propenyl ethyl ester} |
| Shortening | Ac-EFQLQ-{propenyl ethyl ester} |
| Formula | C36H53N7O11 |
| Molar Mass | 759.85 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hussey RJ, et al. A structural study of norovirus 3C protease specificity: binding of a designed active site-directed peptide inhibitor. Biochemistry. 2011 Jan 18;50(2):240-9. |
MAPI
CAS: 1260620-30-1 F: C36H53N7O11 W: 759.85
MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its
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