| Bioactivity | TIBI is a potent and ATP-competitive inhibitor of Rio1 (IC50: 0.09 μM, Ki: 0.05 μM). TIBI enhances the thermostability of the enzyme Rio1[1]. | ||||||||||||
| Target | IC50: 0.09 μM, Ki: 0.05 μM (Rio1) | ||||||||||||
| Name | TIBI | ||||||||||||
| CAS | 1196457-06-3 | ||||||||||||
| Formula | C7H2I4N2 | ||||||||||||
| Molar Mass | 621.72 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Kubiński K, et al. Benzimidazole inhibitors of protein kinase CK2 potently inhibit the activity of atypical protein kinase Rio1. Mol Cell Biochem. 2017 Feb;426(1-2):195-203. |