| Bioactivity | Saracatinib (AZD0530) difumarate is a potent Src inhibitor with IC50 values of 2.7-11 nM for c-Src, Lck, c-YES, Lyn, Fyn, Fgr and Blk, and is selective for other tyrosine kinases. [1]. | ||||||||||||
| Target | IC50: 2.7 nM (Src), 30 nM (v-Abl), 66 nM (EGFR), 200 nM (c-Kit) | ||||||||||||
| Name | Saracatinib difumarate | ||||||||||||
| CAS | 893428-72-3 | ||||||||||||
| Formula | C35H40ClN5O13 | ||||||||||||
| Molar Mass | 774.17 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
||||||||||||
| Reference | [1]. Green TP, et al. Preclinical anticancer activity of the potent, oral Src inhibitor AZD0530. Mol Oncol, 2009, 3(3), 248-261. |
Saracatinib difumarate
CAS: 893428-72-3 F: C35H40ClN5O13 W: 774.17
Saracatinib (AZD0530) difumarate is a potent Src inhibitor with IC50 values of 2.7-11 nM for c-Src, Lck, c-YES, Lyn, Fyn
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.