| Bioactivity | mTORC1-IN-1 (T1) is a rapamycin homologue (rapalog) and selective mTORC1 inhibitor. mTORC1-IN-1 regulates cell growth and metabolism and is implicated in a variety of diseases including cancer. mTORC1-IN-1 targets mTORC1 by binding to the FKBP12-FRB complex (docking score = −11.6 kcal/mol)[1]. |
| Name | mTORC1-IN-1 |
| Formula | C50H77NO12 |
| Molar Mass | 884.15 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lopez J J D, et al. The role of glycerol-water mixtures in the stability of FKBP12-rapalog-FRB complexes [J]. Journal of Molecular Graphics and Modelling, 2023: 108556. |