| Bioactivity | Sakura-6 is a SERT-nnos interaction promoter that significantly increases the SERT-nnos complex, but reduces the level of SERT on the cell surface. Acute injection of Sakura-6 into the dorsal raphe nucleus (DRN) causes depression-like behavior in mice[1]. |
| Name | Sakura-6 |
| CAS | 2490708-79-5 |
| Sequence | {Che}-Ala-Asp-Trp-Val |
| Shortening | {Che}-ADWV |
| Formula | C31H45N5O7 |
| Molar Mass | 599.72 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sun N, et al. Design of fast-onset antidepressant by dissociating SERT from nNOS in the DRN[J]. Science, 2022, 378(6618): 390-398. |
Sakura-6
CAS: 2490708-79-5 F: C31H45N5O7 W: 599.72
Sakura-6 is a SERT-nnos interaction promoter that significantly increases the SERT-nnos complex, but reduces the level o
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