| Bioactivity | SPSB2-iNOS inhibitory cyclic peptide-2 TFA is the TFA salt form of SPSB2-iNOS inhibitory cyclic peptide-2 (HY-P10384). SPSB2-iNOS inhibitory cyclic peptide-2 TFA is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 21 nM. SPSB2-iNOS inhibitory cyclic peptide-2 TFA is reduction-resistant and oxidatively stable[1]. |
| Sequence | cyclo{Trp-Asp-Ile-Asn-Asn-Asn-βAla} |
| Shortening | cyclo{WDINNN-βAla} |
| Formula | C36H49N11O12.xC2HF3O2 |
| Molar Mass | 827.84 (free acid) |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yap BK, et al., Redox-stable cyclic peptide inhibitors of the SPSB2-iNOS interaction. FEBS Lett. 2016 Mar;590(6):696-704. |
SPSB2-iNOS inhibitory cyclic peptide-2 TFA
CAS: F: C36H49N11O12.xC2HF3O2 W: 827.84 (free acid)
SPSB2-iNOS inhibitory cyclic peptide-2 TFA is the TFA salt form of SPSB2-iNOS inhibitory cyclic peptide-2 (HY-P10384). S
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