| Bioactivity | CDK7-IN-28 (CDK7-1276) is a potent CDK7 inhibitor(IC50＜5 nM). CDK7-IN-28 can inhibit proliferation of MDA-MB-468 cell line by blocking cell cycle and inhibiting DNA replication[1]. |
| Invitro | CDK7-IN-28 对 MDA-MB-468 细胞(IC50=2 nM)， HepaRG 细胞(IC50＜10 nM)， NAl-H82 (IC50＜10 nM) 有较好的抗增殖活性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> CDK7-IN-28 相关抗体: Cell Proliferation Assay Cell Line: |
| Formula | C23H27F3N6O |
| Molar Mass | 460.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Светлана Леонидовна ГОРБУНОВА, et al. Cyclin-dependent kinase 7 inhibitors.WO2024063670A1.2023-09-04 |