| Bioactivity | BMS-986189 is a macrocyclic peptide inhibitor of PD-L1 (IC50: 1.03 nM), and can be used for cancer research[1]. |
| CAS | 1629665-96-8 |
| Sequence | {Met}-Tyr-Ala-Asn-Pro-{Dpr}-Leu-{Hyp}-Trp-{Dab}-Trp-{Nle}-{Nle}-Leu-Cys-Gly (Disulfide bridge: Met1-Cys15) |
| Shortening | {Met}-YANP-{Dpr}-L-{Hyp}-W-{Dab}-W-{Nle}-{Nle}-LCG (Disulfide bridge: Met1-Cys15) |
| Formula | C91H131N21O21S |
| Molar Mass | 1887.21 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yang J, et al. Utilization of macrocyclic peptides to target protein-protein interactions in cancer. Front Oncol. 2022 Nov 17;12:992171. |