| Bioactivity | SH514 is an interferon regulatory factor 4 (IRF4) inhibitor with a IC50 value of 2.63 μM. SH514 can be bound to the IRF4-DBD domain with KD values of 1.28 μM. SH514 can be used to study multiple myeloma (MM)[1]. |
| Formula | C32H38N2O4 |
| Molar Mass | 514.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhang JZ, et al. Design, synthesis and biological evaluation of bisnoralcohol derivatives as novel IRF4 inhibitors for the treatment of multiple myeloma. Eur J Med Chem. 2025 Jan 6;285:117240. |