| Bioactivity | SARS-CoV-2-IN-55(compound 65) is a low cytotoxicity inhibtor of SARS-CoV-2 with an IC50 value of 0.3 μM, by the direct interaction with VSV-S pseudoparticles[1]. |
| Target | IC50: 0.3 μM (SARS-CoV-2) |
| Invitro | ARS-CoV-2-IN-55 (10 μM, 24 h) 在 Vero E6 和 A549-ACE2-TMPRSS2 细胞中抑制 SARS-CoV-2 活性，IC50 值为 0.3 μM 和 15.8 μM，同时在 Vero E6-TMPRSS2 细胞中抑制 Wuhan-Hu-1 (IC50=0.28 μM) 和 Omicron BA.1 (IC50=6.24 μM) 活性[1]。 Antiviral Activity assay Cell Line: |
| Name | SARS-CoV-2-IN-55 |
| Formula | C138H136N22O32S6 |
| Molar Mass | 2807.07 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Marta Gargantilla, et al. C‑2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARSCoV‑2 through Interaction with the Viral Spike (S) Protein. J Med Chem. 2023. |
SARS-CoV-2-IN-55
CAS: F: C138H136N22O32S6 W: 2807.07
SARS-CoV-2-IN-55(compound 65) is a low cytotoxicity inhibtor of SARS-CoV-2 with an IC50 value of 0.3 μM, by the direct
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