| Bioactivity | Promazine (Romtiazin) is an antipsychotic and a dopamine receptor D2 antagonist. Promazine inhibits dopaminergic neurotransmission[1][2]. |
| Invitro | Promazine shows KDs of 25, 190 and 8400 nM at the human norepinephrine transporter, serotonin transporter, and dopamine transporter, respectively[3]. |
| Name | Promazine |
| CAS | 58-40-2 |
| Formula | C17H20N2S |
| Molar Mass | 284.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gareri P, et al. Conventional and atypical antipsychotics in the elderly : a review. Clin Drug Investig. 2003;23(5):287-322. [2]. Myers PR, et al. Characterization of a depolarizing dopamine response in a vertebrate neuronal somatic cell hybrid. J Cell Physiol. 1977;91(1):103-118. [3]. Tatsumi M, et al. Pharmacological profile of neuroleptics at human monoamine transporters. Eur J Pharmacol. 1999;368(2-3):277-283. |