Bioactivity | Polyglutamine binding peptide 1 (QBP1) is a peptide inhibitor of polyglutamine (polyQ). Polyglutamine binding peptide 1 inhibits polyQ protein aggregation in vitro and suppresses polyQ-induced cell death in cell culture[1]. |
CAS | 274914-75-9 |
Sequence | Ser-Asn-Trp-Lys-Trp-Trp-Pro-Gly-Ile-Phe-Asp |
Shortening | SNWKWWPGIFD |
Formula | C72H90N16O16 |
Molar Mass | 1435.58 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Yoshitaka Nagai, et al. Prevention of polyglutamine oligomerization and neurodegeneration by the peptide inhibitor QBP1 in Drosophila. Hum Mol Genet. 2003 Jun 1;12(11):1253-9. |