| Bioactivity | EGFR-IN-125 (example 37) is a potent EGFR inhibitor with IC50 values of <0.3 nM, 0.52 nM, 0.5 nM, 0.69 nM and 0.92 nM for EGFR (d746-750/T790M/C779S), EGFR (L858R/T790M/C797S), EGFR (d746-750/C797S), EGFR (L858R/C797S), and EGFR (wild-type), respectively[1]. |
| CAS | 2472802-77-8 |
| Formula | C30H26N8O |
| Molar Mass | 514.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. 冬樹 山本, et al. 7H-pyrrolo [2,3-d] pyrimidine-4-amine derivative. |