| Bioactivity | Plasma kallikrein-IN-2 (Compound 198) is a potent plasma kallikrein (PKal) inhibitor with an IC50 of 0.1 nM. Plasma kallikrein-IN-2 can be used for hereditary angioedema, diabetic macular edema, and diabetic retinopathy research[1]. |
| Target | IC50: 0.1 nM (PKal) |
| Name | Plasma kallikrein-IN-2 |
| Formula | C28H24ClF3N8O3 |
| Molar Mass | 612.99 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ram W. Sabnis, et al. Novel Plasma Kallikrein Inhibitors for Treating Hereditary Angioedema, Diabetic Macular Edema, and Diabetic Retinopathy. ACS Med Chem Lett. 2022 Mar 4;13(4):528-529. |