Bioactivity | Plasma kallikrein-IN-2 (Compound 198) is a potent plasma kallikrein (PKal) inhibitor with an IC50 of 0.1 nM. Plasma kallikrein-IN-2 can be used for hereditary angioedema, diabetic macular edema, and diabetic retinopathy research[1]. |
Target | IC50: 0.1 nM (PKal) |
Name | Plasma kallikrein-IN-2 |
Formula | C28H24ClF3N8O3 |
Molar Mass | 612.99 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ram W. Sabnis, et al. Novel Plasma Kallikrein Inhibitors for Treating Hereditary Angioedema, Diabetic Macular Edema, and Diabetic Retinopathy. ACS Med Chem Lett. 2022 Mar 4;13(4):528-529. |