PeptideDB

Norethindrone acetate-d8

CAS: F: C22H20D8O3 W: 348.51

Norethindrone acetate-d8is the deuterium labeled Norethindrone acetate. Norethindrone acetate is a female hormone used f
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Bioactivity Norethindrone acetate-d8 is the deuterium labeled Norethindrone acetate. Norethindrone acetate is a female hormone used for the research of endometriosis[1].
Invitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Name Norethindrone acetate-d8
Formula C22H20D8O3
Molar Mass 348.51
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Muneyyirci-Delale O, et al. Effect of norethindrone acetate in the treatment of symptomatic endometriosis. Int J Fertil Womens Med. 1998 Jan-Feb;43(1):24-7.;Kaser DJ, et al. Use of norethindrone acetate alone for postoperative suppression of endometriosis