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Piroheptine hydrochloride

CAS: 16378-22-6 F: C22H26ClN W: 339.90

Piroheptine hydrochloride is an anticholinergic agent to inhibit dopamine uptake. Piroheptine hydrochloride prevents los
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Piroheptine hydrochloride is an anticholinergic agent to inhibit dopamine uptake. Piroheptine hydrochloride prevents loss of striatal dopamine induced by MPTP (HY-15608). Piroheptine hydrochloride can be used for research in Parkinson[1].
In Vivo Piroheptine hydrochloride(20 mg/kg;腹腔注射;单剂量,MPTP 注射前 30 分钟)在小鼠模型中抑制 MPTP 的神经毒性[1]。 Animal Model:
Name Piroheptine hydrochloride
CAS 16378-22-6
Formula C22H26ClN
Molar Mass 339.90
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Saitoh T. Suppression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity in mouse brain by piroheptine and trihexyphenidyl. J Neurol Sci. 1988 Feb;83(2-3):161-6.