Bioactivity | Piroheptine hydrochloride is an anticholinergic agent to inhibit dopamine uptake. Piroheptine hydrochloride prevents loss of striatal dopamine induced by MPTP (HY-15608). Piroheptine hydrochloride can be used for research in Parkinson[1]. |
In Vivo | Piroheptine hydrochloride(20 mg/kg;腹腔注射;单剂量,MPTP 注射前 30 分钟)在小鼠模型中抑制 MPTP 的神经毒性[1]。 Animal Model: |
Name | Piroheptine hydrochloride |
CAS | 16378-22-6 |
Formula | C22H26ClN |
Molar Mass | 339.90 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Saitoh T. Suppression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity in mouse brain by piroheptine and trihexyphenidyl. J Neurol Sci. 1988 Feb;83(2-3):161-6. |