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13-Dihydrocarminomycin

CAS: 62182-86-9 F: C26H29NO10 W: 515.51

13-Dihydrocarminomycin (compound D788-12) is the major metabolite of the antitumor antibiotic Carminomycin (HY-B2171). 1
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Bioactivity 13-Dihydrocarminomycin (compound D788-12) is the major metabolite of the antitumor antibiotic Carminomycin (HY-B2171). 13-Dihydrocarminomycin has weak antitumor activity[1][2].
Invitro 13-Dihydrocarminomycin (compound D788-12; 0-1 mM; 48 h) 抑制 L1210 细胞的生长,其 IC50 值为 0.06 µg/mL (120 µM)[1]。 Cell Viability Assay[1] Cell Line:
Name 13-Dihydrocarminomycin
CAS 62182-86-9
Formula C26H29NO10
Molar Mass 515.51
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Yoshimoto A, et al. Anthracycline metabolites from baumycin-producing Streptomyces sp. D788. II. New anthracycline metabolites produced by a blocked mutant strain RPM-5. J Antibiot (Tokyo). 1993 Jan;46(1):56-64. [2]. Poteshnykh AV, et al. Determination of carminomycin and its basic metabolite 13-dihydrocarminomycin by a highly efficient liquid chromatographic method with a fluorescent detector. Antibiotiki. 1982 Nov;27(11):820-3.