| Bioactivity | Piperafizine B exhibits slightly cytotoxicity in moser cells, P388 cells and Vincristine (VCR) (HY-N0488)-resistant P388 cells (IC50s is 23.8, 22.6 and 23.7 μg/mL, respectively). Piperafizine B exhibits synergistic effects with Vincristine, enhances the VCR-induced cytotoxicity and ameliorates the leukemia in mouse model[1]. |
| CAS | 74720-33-5 |
| Formula | C18H14N2O2 |
| Molar Mass | 290.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kamei H, et al., Piperafizines A and B, potentiators of cytotoxicity of vincristine. J Antibiot (Tokyo). 1990 Aug;43(8):1018-20. |
Piperafizine B
CAS: 74720-33-5 F: C18H14N2O2 W: 290.32
Piperafizine B exhibits slightly cytotoxicity in moser cells, P388 cells and Vincristine (VCR) (HY-N0488)-resistant P388
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