| Bioactivity | METTL3-IN-8 (7460-0250) is a potent METTL3 inhibitor. METTL3-IN-8 strongly ameliorates DSS-induced colitis. METTL3-IN-8 can be used Inflammatory bowel disease (IBD) research[1]. |
| CAS | 932512-38-4 |
| Formula | C12H12N4O4 |
| Molar Mass | 276.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yin H, et al. Inhibition of METTL3 in macrophages provides protection against intestinal inflammation. Cell Mol Immunol. 2024 Jun;21(6):589-603. |