| Bioactivity | Menabitan dihydrochloride (SP-204 dihydrochloride) is the dihydrochloride form of Menabitan (HY-160991). Menabitan dihydrochloride is an inhibitor for phosphodiesterase 9 (PDE 9), which acts as a non-opioid analgesic agent. Menabitan dihydrochloride lowers the intraocular pressure in rabbit model[1]. |
| CAS | 58019-50-4 |
| Formula | C37H58Cl2N2O3 |
| Molar Mass | 649.77 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Anaebonam A O. Analytical, formulation development and stability testing of a lyophilized dosage form of menabitan hydrochloride, a new potent analgesic[M]. Massachusetts College of Pharmacy and Health Sciences, 1986. [2]. PITTENGER C, et al., Enhancement of the efficacy of serotonergic psychedelic drugs in the treatment or prevention of certain neuropsychiatric disorders through inhibition of type-9 phosphodiesterases. WO2024107445. [3]. Green K, et al., Acute dose response of intraocular pressure to topical and oral cannabinoids. Proc Soc Exp Biol Med. 1977 Feb;154(2):228-31. |
Menabitan dihydrochloride
CAS: 58019-50-4 F: C37H58Cl2N2O3 W: 649.77
Menabitan dihydrochloride (SP-204 dihydrochloride) is the dihydrochloride form of Menabitan (HY-160991). Menabitan dihyd
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This product is for research use only, not for human use. We do not sell to patients.