| Bioactivity | Penpaxilloids A (Compound 1) is a non-competitive inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC50 value of 8.60 μM. Penpaxilloids A can be isolated from the fungus Penicillium sp. ZYX-Z-143. Penpaxilloids A are also α-glucosidase (α-glucosidase) inhibitors and have anti-inflammatory activity[1]. |
| Formula | C31H37NO7 |
| Molar Mass | 535.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dai LT, et al. Anti-diabetic and anti-inflammatory indole diterpenes from the marine-derived fungus Penicillium sp. ZYX-Z-143. Bioorg Chem. 2024 Apr;145:107205. |