| Bioactivity | PACE4 Inhibitory peptide C23 (Compound C23), a potent peptidomimetic inhibitor, is a PACE4 inhibitor. PACE4 Inhibitory peptide C23e shows antiproliferative effects against PCa cell lines (Ki = 5 nM; IC50 = 25 and 40 μM for DU145 and LNCaP, respectively). PACE4 Inhibitory peptide C23 also blocks tumor growth in vivo in LNCaP xenograft-bearing mice[1]. |
| CAS | 1426656-94-1 |
| Sequence | Ac-{d-Leu}-Leu-Leu-Leu-Arg-Val-Lys-Amba |
| Shortening | Ac-(d-Leu)LLLRVK-Amba |
| Formula | C51H90N14O8 |
| Molar Mass | 1027.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Navals P, et al. Enhancing the Drug-Like Profile of a Potent Peptide PACE4 Inhibitor by the Formation of a Host-Guest Inclusion Complex with β-Cyclodextrin. Mol Pharm. 2023 Sep 4;20(9):4559-4573. |
PACE4 Inhibitory peptide C23
CAS: 1426656-94-1 F: C51H90N14O8 W: 1027.35
PACE4 Inhibitory peptide C23 (Compound C23), a potent peptidomimetic inhibitor, is a PACE4 inhibitor. PACE4 Inhibitory p
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.