| Bioactivity | PKHB1 is a thrombospondin-1 peptide mimic with antitumor effects. PKHB1 induces mitochondrial alterations, ROS production, intracellular Ca2+ accumulation, as well calcium-dependent cell death in breast cancer cells. PKHB1 induces immune system activation through immunogenic cell death induction in breast cancer cells[1]. |
| CAS | 1505523-99-8 |
| Sequence | {d-Lys}-Arg-Phe-Tyr-Val-Val-Met-Trp-Lys-{d-Lys} |
| Shortening | {d-Lys}-RFYVVMWK-{d-Lys} |
| Formula | C68H105N17O12S |
| Molar Mass | 1384.73 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Calvillo-Rodríguez KM, et al. PKHB1, a thrombospondin-1 peptide mimic, induces anti-tumor effect through immunogenic cell death induction in breast cancer cells. Oncoimmunology. 2022 Apr 4;11(1):2054305. |
PKHB1
CAS: 1505523-99-8 F: C68H105N17O12S W: 1384.73
PKHB1 is a thrombospondin-1 peptide mimic with antitumor effects. PKHB1 induces mitochondrial alterations, ROS productio
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.