Bioactivity | NLRP3 / aim2-in-2 is a new potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome dependent cell death. Its IC 50 value is 0.2392 ± 0.0233 μ M。 | |||||||||
Name | NLRP3/AIM2-IN-2 | |||||||||
CAS | 791840-86-3 | |||||||||
Formula | C15H15NO3 | |||||||||
Molar Mass | 257.28 | |||||||||
Appearance | Solid | |||||||||
Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
Storage |
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Reference | [1]. Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194. |