PeptideDB

NLRP3/AIM2-IN-2

CAS: 791840-86-3 F: C15H15NO3 W: 257.28

NLRP3 / aim2-in-2 is a new potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome depen
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Bioactivity NLRP3 / aim2-in-2 is a new potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome dependent cell death. Its IC 50 value is 0.2392 ± 0.0233 μ M。
Name NLRP3/AIM2-IN-2
CAS 791840-86-3
Formula C15H15NO3
Molar Mass 257.28
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194.