GLUT inhibitor-1_product_DataBase

CAS: 2421141-40-2 F: C32H35N7O2 W: 549.67

GLUT inhibitor-1 is a potent and orally active inhibitor of glucose transporters, targeting both GLUT1 and GLUT3, with I

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

GLUT inhibitor-1 is a potent and orally active inhibitor of glucose transporters, targeting both GLUT1 and GLUT3, with IC50s of 242 nM and 179 nM, respectively. GLUT inhibitor-1 has the potential for the reaesrch of cancers and autoimmune diseases[1].

In Vivo

Summary of the pharmacokinetic parameters of GLUT inhibitor-1 (compound 15b; 30 mg/kg) in mouse and rat[1]. Parameter

Name

GLUT inhibitor-1

CAS

2421141-40-2

Formula

C32H35N7O2

Molar Mass

549.67

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Liu KG, et al. Discovery and Optimization of Glucose Uptake Inhibitors. J Med Chem. 2020;63(10):5201-5211.

PeptideDB

GLUT inhibitor-1

CAS: 2421141-40-2 F: C32H35N7O2 W: 549.67