| Bioactivity | NFAT Inhibitor (VIVIT peptide) is a cell-permeable peptide inhibitor of nuclear factor of activated Tcells (NFAT) that selectively inhibits calcineurin-mediated dephosphorylation of NFAT[1][2]. | ||||||
| Invitro | NFAT Inhibitor treatment significantly inhibits nuclear translocation of NFATc1 for 24 hours. Long-term treatment with VIVIT significantly inhibits the cytoplasmic levels of cathepsin K, TRAP, and MMP-9[2]. Western Blot Analysis[2] Cell Line: | ||||||
| Name | NFAT Inhibitor-1 | ||||||
| CAS | 249537-73-3 | ||||||
| Sequence | Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu | ||||||
| Shortening | MAGPHPVIVITGPHEE | ||||||
| Formula | C75H120N20O22S | ||||||
| Molar Mass | 1685.94 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
NFAT Inhibitor-1
CAS: 249537-73-3 F: C75H120N20O22S W: 1685.94
NFAT Inhibitor (VIVIT peptide) is a cell-permeable peptide inhibitor of nuclear factor of activated Tcells (NFAT) that s
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