| Bioactivity | OVA Peptide TFA is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I MHC molecule, H-2Kb. | ||||||
| Invitro | TAP1-I- and C57BL/6 macrophages may process Crl-OVA and full-length OVA in different cellular compartments and that the protein context of the OVA Peptide epitope influences the extent of TAP-independent processing for MHC class I presentation. OVA Peptide epitope is presented with a differential dependence on the TAP transporter depending on the protein context of the OVA epitope: OVA Peptide contained within the MBPCrl-OVA or Crl-OVA bacterial fusion proteins is presented with little dependence on the TAP transporter, while OVA Peptide contained within full-length ovalbumin is largely dependent on the TAP transporter, regardless of whether recombinant OVA is expressed in bacteria or the native protein is coupled to polystyrene beads[1]. | ||||||
| Name | OVA Peptide TFA | ||||||
| CAS | 1262751-08-5 | ||||||
| Sequence | Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu | ||||||
| Shortening | SIINFEKL | ||||||
| Formula | C47H75F3N10O15 | ||||||
| Molar Mass | 1077.15 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |