| Bioactivity | Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage[1]. |
| Invitro | Mca-(ala7,lys(dnp)9)-bradykinin is also a substrate for neprilysin, but is hydrolyzed 10-fold more efficiently by ECE-1, making this substrate selective for ECE-1[1]. |
| Name | Mca-(ala7,lys(dnp)9)-bradykinin |
| CAS | 323577-36-2 |
| Shortening | {MOCAc}-RPPGFSAFK-{DNP} |
| Formula | C66H81N15O19 |
| Molar Mass | 1388.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Mca-(ala7,lys(dnp)9)-bradykinin
CAS: 323577-36-2 F: C66H81N15O19 W: 1388.44
Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The inc
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.